By leveraging scientific advances in HIV prevention, diagnosis, treatment, and care, and by forming partnerships with communities and researchers across the country, we are well-positioned to reduce the number of new HIV transmissions in the United States and improve the longevity and quality of life for people with HIV.
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Our study participants who are living with and without HIV have contributed to over 35 years of groundbreaking discoveries in the field of HIV research. Our study participants have been critical to life-saving discoveries, and their continued participation is central to further HIV research.

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Since 1984, more than 12,000 people have participated in the Multicenter AIDS Cohort Study and the Women’s Interagency HIV Study (now known as MACS/WIHS Combined Cohort Study). Investigators can request access to over 35 years of data and biospecimens including serum, plasma, cells, hair, and urine.

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Psychosocial aspects of AIDS risk

Psychopharmacol Bull 1986

Ostrow, D.G., Joseph, J., Monjan, A., Kessler, R., Emmons, C., Phair, J., Fox, R., Kingsley, L., Dudley, J., Chmiel, J.S. and Van Raden, M.

The Women’s Interagency HIV Study. WIHS Collaborative Study Group

Epidemiology 1998

Barkan, S. E., Melnick, S. L., Preston-Martin, S., Weber, K., Kalish, L. A., Miotti, P., Young, M., Greenblatt, R., Sacks, H., Feldman, J. and Grp, WIHS Collaborative Study

Characteristics Of The MACS-WIHS Combined Cohort Study: Opportunities For Research On Aging With Hiv In The...

Am J Epidemiol, 2021

Gypsyamber D'Souza, Fiona Bhondoekhan, Lorie Benning, Joseph B Margolick, Adebola A Adedimeji, Adaora A Adimora, Maria L Alcaide, Mardge H Cohen, Roger Detels, M Reuel Friedman, Susan Holman, Deborah J Konkle-Parker, Daniel Merenstein, Igho Ofotokun, Frank Palella, Sean Altekruse, Todd T Brown, Phyllis C Tien

The Changing Science of HIV Epidemiology in the United States

Am J Epidemiol 2019

Gypsyamber D'Souza, Elizabeth T Golub, Stephen J Gange

The Women’s Interagency HIV Study: an Observational Cohort Brings Clinical Sciences to the Bench

Clin Diagn Lab Immunol 2005

Bacon, M. C., von Wyl, V., Alden, C., Sharp, G., Robison, E., Hessol, N., Gange, S., Barranday, Y., Holman, S., Weber, K. and Young, M. A.

How has the MWCCS changed HIV science over the past three decades? LEARN MORE