Aim 1: Expand the STAR cohort as a platform for high priority, collaborative HIV\/sexual health science for reproductive age women. Using its existing structure and\u00a0track record\u00a0of engaging a large and diverse population, we will longitudinally continue and expand the cohort,\u00a0leveraging\u00a0its assessments, specimen collections, data management, and leadership structure<\/span>.<\/span>\u00a0<\/span><\/p>\n Aim 2: Leverage resources through the Scientific Administrative Core (SAC), Data Management and Analysis Core (DMAC), and Community Engagement and Implementation Core (CEIC) to promote rigorous, community-informed science. We will establish\u00a0procedures to support (a) the overall management, communication, coordination, and scientific direction of STAR; (b) rigorous data collection and analytic support; and (c) unified community engagement. STAR will be coordinated by the SAC to support an executive committee, scientific leadership group, and advisory groups, will integrate with its cores\/projects, and will provide mentorship to\u00a0ESIs.<\/span>\u200b<\/span>\u00a0<\/span>\u00a0<\/span><\/p>\n Aim 3:\u00a0Test a unifying research hypothesis that\u00a0HIV and\u00a0reproductive transitions have intersecting effects on vascular comorbidities and sexual health via interlinked projects. Using the cohort\u2019s longitudinal data\/specimens across reproductive transitions, we will investigate vascular endothelial function, coronary artery calcium scores, and hypertension to address cardiovascular health; health behaviors, sexually transmitted infections (STIs), and inflammation to address sexual health. The projects will\u00a0utilize\u00a0data and samples collected as part of\u00a0STAR. If\u00a0additional\u00a0assessments involving human subjects are proposed in any STAR-linked sub-study, an amendment or a new study will be\u00a0submitted\u00a0to the IRB.<\/span><\/p>\n <\/p>\n STAR 2.0 Study Aims Aim 1: Expand the STAR cohort as a platform for high priority, collaborative HIV\/sexual health science for reproductive age women. Using its existing structure and\u00a0track record\u00a0of engaging a large and diverse population, we will longitudinally continue and expand the cohort,\u00a0leveraging\u00a0its assessments, specimen collections, data management, and leadership structure.\u00a0 Aim 2: Leverage […]<\/p>\n","protected":false},"author":2,"featured_media":215,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-36","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/statepi.jhsph.edu\/star\/wp-json\/wp\/v2\/pages\/36","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/statepi.jhsph.edu\/star\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/statepi.jhsph.edu\/star\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/statepi.jhsph.edu\/star\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/statepi.jhsph.edu\/star\/wp-json\/wp\/v2\/comments?post=36"}],"version-history":[{"count":7,"href":"https:\/\/statepi.jhsph.edu\/star\/wp-json\/wp\/v2\/pages\/36\/revisions"}],"predecessor-version":[{"id":1032,"href":"https:\/\/statepi.jhsph.edu\/star\/wp-json\/wp\/v2\/pages\/36\/revisions\/1032"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/statepi.jhsph.edu\/star\/wp-json\/wp\/v2\/media\/215"}],"wp:attachment":[{"href":"https:\/\/statepi.jhsph.edu\/star\/wp-json\/wp\/v2\/media?parent=36"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}LINK<\/a> to STAR 1.0 Study Aims<\/h2>\n","protected":false},"excerpt":{"rendered":"