{"id":5225,"date":"2025-10-20T17:35:43","date_gmt":"2025-10-20T21:35:43","guid":{"rendered":"https:\/\/statepi.jhsph.edu\/mwccs\/?page_id=5225"},"modified":"2026-02-06T19:32:06","modified_gmt":"2026-02-07T00:32:06","slug":"substudy-science","status":"publish","type":"page","link":"https:\/\/statepi.jhsph.edu\/mwccs\/substudy-science\/","title":{"rendered":"Substudy Science"},"content":{"rendered":"<p><a href=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/uploads\/2025\/12\/Substudy-Enrollment-Overview-Vertical_12.15.25.pdf\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-5310 size-full\" src=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/uploads\/2025\/12\/MWCCS_Substudies_Overview_Vertical_12.15.25-scaled.jpg\" alt=\"MWCCS Study Wide Substudies: Data on many key intensive measurements are now available for thousands of participants! Contains substudy overview details for the thousands of participants who have enrolled in different substudies.\" width=\"1976\" height=\"2560\" srcset=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/uploads\/2025\/12\/MWCCS_Substudies_Overview_Vertical_12.15.25-scaled.jpg 1976w, https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/uploads\/2025\/12\/MWCCS_Substudies_Overview_Vertical_12.15.25-232x300.jpg 232w, https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/uploads\/2025\/12\/MWCCS_Substudies_Overview_Vertical_12.15.25-791x1024.jpg 791w, https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/uploads\/2025\/12\/MWCCS_Substudies_Overview_Vertical_12.15.25-768x995.jpg 768w, https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/uploads\/2025\/12\/MWCCS_Substudies_Overview_Vertical_12.15.25-1186x1536.jpg 1186w, https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/uploads\/2025\/12\/MWCCS_Substudies_Overview_Vertical_12.15.25-1581x2048.jpg 1581w\" sizes=\"auto, (max-width: 1976px) 100vw, 1976px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<h1>View visual summaries for individual substudies<\/h1>\n<h4><a href=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/uploads\/2025\/10\/Substudy_visualabstract_CIDI_10.23.25.pdf\" rel=\"noopener\">Mental Health and Substance Use Substudy (PDF)<\/a><\/h4>\n<h4><a href=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/uploads\/2025\/12\/MWCCS_PFT_Substudy_Visual_Abstract_12.09.25.pdf\" rel=\"noopener\">Pulmonary Function Substudy (PDF)<\/a><\/h4>\n<h4><a href=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/uploads\/2025\/12\/MWCCS_Hearing_and_Balance_Substudy_VisualAbstract_12.15.25.pdf\" rel=\"noopener\">Hearing and Balance Substudy (PDF)<\/a><\/h4>\n<h4><a href=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/uploads\/2025\/12\/MWCCS_Echo_Substudy_VisualAbstract_12.8.25.pdf\" rel=\"noopener\">Echocardiogram Substudy (PDF)<\/a><\/h4>\n<h4><a href=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/uploads\/2025\/12\/MWCCS_Fibroscan_Substudy_VisualAbstract_12.8.25.pdf\" rel=\"noopener\">Fibroscan\u00ae Substudy (PDF)<\/a><\/h4>\n<h4><a href=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/uploads\/2025\/12\/MWCCS_Brief_Cognitive_Function_Substudy_VisualAbstract_12.08.25.pdf\" rel=\"noopener\">Brief Cognitive Substudy (PDF)<\/a><\/h4>\n<h4><a href=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/uploads\/2025\/12\/MWCCS_Full_Cognitive_Function_Substudy_VisualAbstract_12.08.25.pdf\" rel=\"noopener\">Full Cognitive Substudy (PDF)<\/a><\/h4>\n<h4><a href=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/uploads\/2025\/12\/MWCCS_Tooth_Count_Substudy_VisualAbstract_12.09.25.pdf\" rel=\"noopener\">Tooth Count Substudy (PDF)<\/a><\/h4>\n<h4><a href=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/uploads\/2025\/12\/MWCCS_Microbiome_Substudy_VisualAbstract_12.10.25.pdf\" rel=\"noopener\">Microbiome Substudy (PDF)<\/a><\/h4>\n<h3><script type=\"text\/javascript\">\r\ndocument.addEventListener(\"DOMContentLoaded\", function(event) { \r\n\tjQuery( '#slider-pro-3-5228' ).sliderPro({\r\n\t\t\/\/width\r\n\t\t\t\twidth: \"100%\",\r\n\t\t\t\t\r\n\t\t\/\/height\r\n\t\t\t\tautoHeight: true,\r\n\t\t\t\t\r\n\t\t\/\/auto play\r\n\t\t\t\tautoplay:  true,\r\n\t\tautoplayOnHover: 'none',\r\n\t\t\t\t\t\t\t\tautoplayDelay: 10000,\r\n\t\t\r\n\t\t\r\n\t\tarrows: true,\r\n\t\tbuttons: true,\r\n\t\tsmallSize: 500,\r\n\t\tmediumSize: 1000,\r\n\t\tlargeSize: 3000,\r\n\t\tfade: true,\r\n\t\t\r\n\t\t\/\/thumbnail\r\n\t\tthumbnailArrows: true,\r\n\t\tthumbnailWidth: 120,\r\n\t\tthumbnailHeight: 120,\r\n\t\t\t\t\t\tthumbnailsPosition: 'bottom',\r\n\t\t\t\t\t\tcenterImage: true,\r\n\t\timageScaleMode: 'cover',\r\n\t\tallowScaleUp: true,\r\n\t\t\t\tstartSlide: 0,\r\n\t\tloop: true,\r\n\t\tslideDistance: 5,\r\n\t\tautoplayDirection: 'normal',\r\n\t\ttouchSwipe: true,\r\n\t\tfullScreen: false,\r\n\t});\r\n});\r\n<\/script>\r\n\r\n\t\t<div id=\"slider-pro-3-5228\" class=\"slider-pro\">\r\n\t\t\t<!---- slides div start ---->\r\n\t\t\t<div class=\"sp-slides\">\r\n\t\t\t\t\t\t\t\t\t\t<div class=\"sp-slide\">\r\n\t\t\t\t\t\t\t<img decoding=\"async\" class=\"sp-image\" loading=\"lazy\" alt=\"Visual abstract showing details about what was measured, who data was collected from and what we can learn from the data collected in the Mental Health and Substance Use Substudy. Data was collected from October 2021 to September 2025.\" src=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/plugins\/ultimate-responsive-image-slider\/assets\/css\/images\/blank.gif\" data-src=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/uploads\/2025\/10\/CIDI_visualabstract_10.23.25-scaled.jpg\" \/>\r\n\r\n\t\t\t\t\t\t\t\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"sp-slide\">\r\n\t\t\t\t\t\t\t<img decoding=\"async\" class=\"sp-image\" loading=\"lazy\" alt=\"Visual abstract showing details about what was measured, who data was collected from and what we can learn from the data collected in the Pulmonary Function Substudy. Data was collected from October 2021 to September 2025.\" src=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/plugins\/ultimate-responsive-image-slider\/assets\/css\/images\/blank.gif\" data-src=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/uploads\/2025\/12\/PFT_visualabstract_12.09.25-scaled.jpg\" \/>\r\n\r\n\t\t\t\t\t\t\t\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"sp-slide\">\r\n\t\t\t\t\t\t\t<img decoding=\"async\" class=\"sp-image\" loading=\"lazy\" alt=\"Visual abstract showing details about what was measured, who data was collected from and what we can learn from the data collected in the Hearing and Balance Substudy. Data was collected from October 2020 to September 2022.\" src=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/plugins\/ultimate-responsive-image-slider\/assets\/css\/images\/blank.gif\" data-src=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/uploads\/2025\/12\/HearingandBalance_visualabstract_12.15.25-scaled.jpg\" \/>\r\n\r\n\t\t\t\t\t\t\t\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"sp-slide\">\r\n\t\t\t\t\t\t\t<img decoding=\"async\" class=\"sp-image\" loading=\"lazy\" alt=\"Visual abstract showing details about what was measured, who data was collected from and what we can learn from the data collected in the Echocardiogram Substudy. Data collection from October 2022 to September 2026.\" src=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/plugins\/ultimate-responsive-image-slider\/assets\/css\/images\/blank.gif\" data-src=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/uploads\/2025\/12\/Echo_visualabstract_12.08.25-scaled.jpg\" \/>\r\n\r\n\t\t\t\t\t\t\t\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"sp-slide\">\r\n\t\t\t\t\t\t\t<img decoding=\"async\" class=\"sp-image\" loading=\"lazy\" alt=\"Visual abstract showing details about what was measured, who data was collected from and what we can learn from the data collected in the Fibroscan Substudy. Data collection from October 2020 to September 2026.\" src=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/plugins\/ultimate-responsive-image-slider\/assets\/css\/images\/blank.gif\" data-src=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/uploads\/2025\/12\/Fibroscan_visualabstract_12.08.25-scaled.jpg\" \/>\r\n\r\n\t\t\t\t\t\t\t\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"sp-slide\">\r\n\t\t\t\t\t\t\t<img decoding=\"async\" class=\"sp-image\" loading=\"lazy\" alt=\"Visual abstract showing details about what was measured, who data was collected from and what we can learn from the data collected in the Brief Cognitive Substudy. Data collection from October 2021 to September 2026.\" src=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/plugins\/ultimate-responsive-image-slider\/assets\/css\/images\/blank.gif\" data-src=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/uploads\/2025\/12\/Brief_Cognitive_visualabstract_12.08.25-scaled.jpg\" \/>\r\n\r\n\t\t\t\t\t\t\t\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"sp-slide\">\r\n\t\t\t\t\t\t\t<img decoding=\"async\" class=\"sp-image\" loading=\"lazy\" alt=\"Visual abstract showing details about what was measured, who data was collected from and what we can learn from the data collected in the Full Cognitive Substudy. Data collection from October 2022 to September 2026.\" src=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/plugins\/ultimate-responsive-image-slider\/assets\/css\/images\/blank.gif\" data-src=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/uploads\/2025\/12\/Full_Cognitive_visualabstract_12.08.25-scaled.jpg\" \/>\r\n\r\n\t\t\t\t\t\t\t\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"sp-slide\">\r\n\t\t\t\t\t\t\t<img decoding=\"async\" class=\"sp-image\" loading=\"lazy\" alt=\"Visual abstract showing details about what was measured, who data was collected from and what we can learn from the data collected in the Tooth Count Substudy. Data collection from October 2022 to September 2026.\" src=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/plugins\/ultimate-responsive-image-slider\/assets\/css\/images\/blank.gif\" data-src=\"https:\/\/statepi.jhsph.edu\/mwccs\/wp-content\/uploads\/2025\/12\/ToothCount_visualabstract_12.09.25-scaled.jpg\" \/>\r\n\r\n\t\t\t\t\t\t\t\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"sp-slide\">\r\n\t\t\t\t\t\t\t<img decoding=\"async\" class=\"sp-image\" loading=\"lazy\" alt=\"Visual abstract showing details about what was measured, who data was collected from and what we can learn from the data collected in the Microbiome Substudy. 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