CKiD Investigator Resources

The Chronic Kidney Disease in Children (CKiD) study welcomes collaborations with investigators and with other cohorts. If you are an investigator interested in collaborating with CKiD, below is information on how to propose a new research proposal, request data and/or specimens, develop and submit a manuscript, and comply with CKiD publication requirements.

New Research Proposal/Analysis

Step 1: Develop research proposal

types of concept sheet proposals

Step 2: Complete the latest CKiD Study Concept Sheet Submission Form

Step 3: Submit Concept Sheet to CKiD for Subcommittee and Steering Committee Review

Step 4: Concept Sheet Review

concept sheet review timeline

Step 5: Concept Sheet Outcome

Based on the Concept Sheet Review Process, investigators will receive one of four responses:

Step 6: README Number Assignment

Once Concept Sheet is approved:

Submitting a Revised Concept Sheet or Amdendment

Investigators may submit a revised concept sheet based on comments from the reviewers and Steering Committee. To submit a revision for review, please complete the following:

Investigators may submit an addendum or amendment to a previously approved concept sheet if they are requesting additional data or specimens. The concept sheet will retain the same README number assigned to the intial project. To submit and amendment for review, please complete the following:

Requesting an Analytic CKiD Dataset/Obtaining a Data Use Agreement

As indicated on the concept sheet submission form, an investigator can request the creation of a limited data set to complete the analysis independently.

  • Must complete a Data Use Agreement (DUA) between investigator's institution and Johns Hopkins (on behalf of CKiD)
    1. Investigator submits the DUA to their own institution's research administration to obtain the appropriate signatures
    2. Send partially executed DUA back to CKiD to submit to JHU Research Administration
  • After fully executed DUA is completed, KIDMAC will prepare the dataset and codebook for the variables included in investigator's approved concept sheet
  • If an investigator is completing the analysis independently and wants to examine additional variables beyond those requested in their approved concept sheet, an addendum will need to be submitted and reviewed. To submit an addendum request, an investigator will need to complete the concept sheet submission form, list the additional variables requested and check "addendum" as the submission type and include the assigned README number.

    Requesting Specimens

    Before obtaining CKiD specimens from the NIDDK Central Repository, an investigator must complete these steps:

    Annual Progress Report

    All investigators with approved CKiD concept sheets are required to submit an annual progress report.

    Publication Requirements

    CKiD Publication Acknowledgment

    All publications that use data or samples supplied by CKiD must include the following acknowledgment:

    Data in this manuscript were collected by the Chronic Kidney Disease in children prospective cohort study (CKiD) with clinical coordinating centers (Principal Investigators) at Children's Mercy Hospital and the University of Missouri - Kansas City (Bradley Warady, MD) and Children's Hospital of Philadelphia (Susan Furth, MD, PhD), Central Biochemistry Laboratory (George Schwartz, MD) at the University of Rochester Medical Center, and data coordinating center (Alvaro Muñoz, PhD and Derek Ng, PhD) at the Johns Hopkins Bloomberg School of Public Health. The CKiD Study is supported by grants from the National Institute of Diabetes and Digestive and Kidney Diseases, with additional funding from the Eunice Kennedy Shriver National Institute of Child Health and Human Development, and the National Heart, Lung, and Blood Institute (U01-DK-66143, U01-DK-66174, U24-DK-082194, U24-DK-66116). The CKiD website is located at https://statepi.jhsph.edu/ckid.

    Manuscript Notification

    Lead authors are responsible for notifying KIDMAC when a manuscript has been accepted for publication.

    PMCID Assignment

    Investigators are required to ensure that any publication that uses CKiD data or samples has a PubMed Central Reference Number (PMCID) assigned to it. The PMCID is a unique reference number that is distinct from the PMID number assigned in PubMed. Some journals will submit manuscripts on behalf of authors to be deposited in PubMed Central (see list here).

    It is the responsibility of the lead author to submit published manuscript to the NIHMS system to obtain a PMCID if the journal does not submit manuscripts directly. This process is outlined in more detail in the CKiD Publication Policy. Please contact KIDMAC with any questions about this process.